Universal Microbe Detection™ (UMD) is used for the identification of bacteria, yeasts and other fungi from a broad range of sample types including blood, heart valve tissue and synovial fluid. UMD is a complete system for detection and identification of pathogens. It includes reagents for nucleic acid purification for concentrating and purifying pathogen nucleic acids, DNA-free PCR reagents for amplification of 16S and 18S rRNA genes, and sequencing primers for identification of the organism(s).
Currently there are more than 345 pathogens that have been identified in biologic samples in various studies utilizing UMD or Molzym's SepsiTest products. Sequencing of amplicons with an online homology Blast Search is an option for identification of pathogens. The Molzym sequence database includes only validated bacterial and fungal sequences.
In Europe and Asia studies using the UMD reagents have been performed for sepsis, endocarditis, joint infections and meningitis. For more information, see Applications.